With
Shared Knowledge…More Kids will Heal!!!
Do Not do anything without your doctor’s knowledge and
consent. What worked for my child will not necessarily work for yours. Please
do not act based on information contained in this website, but from a
thoroughly educated place, including your health care professionals opinions.
The producer of this website accepts no responsibility or liability for the
consequences of any actions taken on the basis of the information provided in
this website. Any views and opinions are solely those of the author and do not
represent a collaborative conclusion, and should not be interpreted as such.
Go
forth & heal!
First…THANK YOU SOOOOO MUCH to Heather who took these great notes!
One of my doctors told me about them…she had gotten them from one of
her new
patients. I e-mailed Heather & she sent them to me & here
they are. I chose
not to “do” anything
except pass them on to you. They have not been checked
for accuracy but are simply her notes from the conference. So please
assess them
based on that! (Okay…I originally launched it without input earlier today…but
now as I am reading through it, I can’t help but put in my 2 cents…You will
find them in purple!) but I am not confirming anything…just commenting.
Dr. Buttar (Boo-TAR)– Oct. 1st, 2004 DefeatAutismYesterday Conference
6:15-10:30pm
Methods of Mercury Toxicity
-breathing in toxic vapors
-in utero-1 out of 8 women are mercury toxic because of amalgams
and other things
-Fish Industry is about 10% of the cause of mercury poisoning
-Immunizations, epidurals, anesthesia
-Lead and all other metals are not nearly as neurotoxic as
mercury. Only Uranium and Plutonium are as toxic, yet they are not
prevalent in our environment like mercury
-Most of us suffer from CHRONIC mercury toxicity and it’s effects
-Mercury is heavily correlated with Cancer and Heart disease
patients
-Cancer and heart disease account for 8 out of 10 deaths from all
diseases, wars, illnesses, injuries combined
-Autism is now 1 in 149 kids
-Vaccines still have Mercury (Hg) because the pharmaceutical
companies legally don’t have to tell you how much is in there during
manufacturing. They are only required to tell you if they preserve it
with mercury. So, plenty of mercury is still in the vaccines even if you
read the label and it shows none.
-Check for ongoing toxicity coming from the environment like where
you live and the direction the wind blows. Is there combustion of fossil
fuels even several hours away but the wind is blowing toward you?
-There is no other substance, not vitamin deficiencies, lead,
yeast, food allergies, etc. that could possibly cause a normally developing
child who is speaking words by 11-12 months, to lose all speech and become
autistic by 14-21 months. The only thing that could have caused this
severe of brain damage is mercury (Hg.)
Hepatitis B Vaccination
-Useful for IV Drug Users, Prostitutes, and Health Care Providers
-A person needs 3 shots to become immunized to anything
-With Hep B, we need boosters because it only lasts 8-10 years
-We give newborns a shot of Hep B in the first 12 hours of life
-Therefore, are we really concerned that our baby will become an
IV Drug User, Prostitute or even a Health Care Provider in the first 10 years
of life when neurological development is so crucial?
Biliary Tract
-The biliary tract is God’s way of detoxing yourself. God
put it in our bodies to have toxins, like heavy metals, move out that
way. But, the biliary tract is NOT functional until after the first year
of life, so our kids have no way of detoxing themselves until after age 1
(I hear this over & over from all the Naturopathic…awesome
doctors I have gone thru)
TD-DMPS - misc. info
Okay…Okay…Okay…I am going to say it hear & will say it to Dr Buttar (like I did during my interview with him in July) personally next week…When you read what is below, you need to remember…One of Dr Buttar’s specialties is removing toxins (esp. mercury) from the body. Because of that he has had great success with kids with autism. His specialty is not RECOVERING THE BRAIN once it is detoxed…SO DO NOT allow anything he says dissuade you if you have an older child! He is simply not willing to say he has arrived at complete recovery beyond the age of 9… yet, because he hasn’t had it happen…yet! This is where the work of Dr. Amy Yasko comes in (some of her fastest recoveries are with older children)…go to: AutismAnswer.com & read about RNA & special protocols (at a certain time in the healing process) to re-myelinate the damaged nerves. Then there are places like The Brain Institute & NACD.org who specialize in activities to heal the brain…& all kinds of other things…so Go Forth & Heal! & read on…
-For severe cases of ASD, TD-DMPS is only effective for children
under the age of 9 (for a complete cure). It has helped adults and will
help everyone who is metal poisoned, especially mercury poisoned.
-He has had children over the age of 11 with mild autism or adhd,
recover completely
-Viral Titres, allergies metabolic problems like thyroid
disorders, which are common in our kids, immune system problems, are all from
mercury poisoning
-Kids on TD-DMPS tend to have growth spurts like crazy, like 2 of
his patients who grew 6 inches in 6 months after getting rid of the poison in
their bodies
-Getting rid of the poison, gets rid of the symptoms of autism and
the health problems too
-Transdermal DMPS is a ratio of 4 parts glutathione to 1 part DMPS
conjugated with amino acids (My
understanding from Tom at College Pharmacy is that it is actually the amino
acids that make up glutathione rather than glut itself)
-The glutathione allows the sulfhydryl to work better and is
really a great substance in general especially for chelation and is in every
cell of our body and
diminishes with old age (healthy elderly people are found to have
more of it present in their cells)
-You may see a worsening of behavior in an ASD child approximately
1-2 months into usage with DMPS, but you may also see improvement in social and
speech areas. This improvement is evidence that it is working and you
must keep the dose to as maximum as possible even with a rash because the rashes
and behavior are temporary. If you stop usage, you will not start back
where you left off.
(one way to help keep the liver & kidneys functioning well is
by adding homeopathics: Unda 2, 48, 458 or HEEL Detox) which should help limit exacerbations
of behaviors & addressing methylation should help with this too!
Autism Commonalities
These kids are always:
1. Mercury Toxic
2. Extremely
Bright (Gordon &
Yasko say this too!)
Amalgams
Each new filling is leaking 500
nanograms of mercury
per day. Old fillings, even from 20-year old cadavers are leaking about 9
nanograms per day of mercury.
Case Study – Karen
Karen came in to Dr. Buttar and said she had seen 16 doctors and
had been tested for everything and nobody could help her. She had a lot
of pain, strange systemic problems, severe depression, headaches, etc. and said
to Dr. Buttar while patting her purse, “If you can’t help me, I will help
myself.” Not sure what was inside her purse – gun or maybe pills.
Dr. Buttar said that he could definitely help her and that she was
probably just poisoned with mercury (Hg). She said she had already been
tested for mercury levels and had taken DMSA challenge tests and that she did
not show high mercury levels. Her level of Hg was 2.3 at the time.
She again asked Dr. Buttar if he was still sure that he could treat her?
He made her sign an agreement that she would not try to kill herself and that
they needed to try his protocol and they would find out in time if it was going
to help her. He put Karen on TD-DMPS.
Here’s the date and Karen’s Hg levels:
Early year 2000
2.3
March
2000
2.8
October
2000 9.4
March
2001
19 – her mercury level was high yet symptoms had diminished greatly
October
2001 27 – She
is almost symptom free at this point yet her mercury levels are off the chart
Mid
2002
8.7 – Two and a half years into treatment, she has no symptoms and Hg levels
are finally coming down but still elevated. She is still on TD-DMPS at this
point.
Summary: Karen had only one amalgam in her mouth but had worked in
a chemical plant in her late 20’s and transported mysterious items in a truck
and that is when her symptoms started to appear. Buttar believes she was
exposed to high Hg levels at this job. She recovered completely on
TD-DMPS for almost 3 years.
Abi (AB-ee) Buttar
His son was born Jan. 1999, after he had given up on treating ASD
kids in his practice because they were too difficult to treat. “God must
have given me Abi so I could learn how to treat other children” and come up
with this formula (TD-DMPS). Abi was diagnosed with autism and treated
with TD-DMPS starting at age 3 and had no diet change. He was non-verbal,
except for saying continually, “Day, Day, Day, Day.” Five months to
chelation with TD-DMPS, Abi was talking full sentences. With hair
analysis of his son, only arsenic, antimony, tin and nickel showed up.
Mercury in fecal and urine at first testing was at a 1.9. This is typical
of ASD kids on his protocol to show low levels of mercury naturally coming out
because they cannot detox themselves. Normal kids have high levels of mercury
in their hair and autistic kids have very low levels. During continuous
chelation treatment, as those 4 metals go up high and then come down, that is
when the mercury levels first start to appear. As the mercury levels
start going up, you must be consistent with the treatment! TD-DMPS
was continued until the Hg levels spiked and then went all the way down.
He now chelates his son for one month every year because of a flawed
detoxification pathway that is evident in all children with ASD.
ASD is not autism, it is mercury poisoning because our kids cannot detoxify themselves.
-With DMPS oral, Abi’s Hg levels were off the charts as compared
to when he used DMSA oral. There is a tremendous difference in how the
two chelate.
-Some parents quit the TD-DMPS chelating process after 2 months
because of yeast flare-ups. The key to getting the mercury to come out
and why my protocol works at all: is using it Continuously! If yeast shows up, then you treat it, but you keep the
DMPS dosage as close to maximum as possible because it is the fire causing all
the other problems. You must get the poison out so you can then see what
is left and deal with the other problems that remain after eliminating the main
one. You have no idea how much mercury is in a body until you remain on
the protocol for a while. The other metals have to come out before the
mercury will start to budge. If you quit, then you will not get to the
mercury and you may not start back where you left off. He originally had
to chelate his son every other day because of visitation rights during his
nasty divorce from his ex-wife. However, in the process of healing his
son, he did experiment with chelation every day and did not get the same
results and pulled out less mercury than when he chelated every other
day. This is because he believes the body has to redistribute the mercury
and needs 48 hours to do it. You chelate a little bit out every 48 hours.
AMT Pharmacy
Dr. Buttar originally used College pharmacy owned by
Tom----. College pharmacy followed Dr. Buttar’s protocol on making
DMPS. Now, College pharmacy, located in North Carolina, is called AMT
Pharmacy. (You can call AMT’s Melanie Gentile at (866) 828-8203 X156 or locally at (704) 892-1874 (this is a fax # & as you can
probably imagine they are incredibly busy so PLEASE be patient with them…ALSO,
TO EXPEDITE YOUR ORDER in addition to the Rx make sure it contains: recipient
shipping address, credit card info & DOB of patient otherwise it will take
an extra week for them to call you back & get this info) to order TD-DMPS. The approximate
cost for a 45-pound child is $160 for a two-month supply and they can ship the
prescription to you once your doctor calls it in. This info was not given out
at the conference. Dr. Buttar was not there to sell anything and spoke at this
conference for free and insisted on having no charge for the parents and all
attendees.)
Types of Rashes with DMPS
1. Oxidative
Reaction – like a burn because DMPS cannot be stabilized easily and Dr. Buttar
is the first to come up with a way to do this. AMT pharmacy is the best
because they follow Dr. Buttar’s protocol for stabilizing (making) the
TD-DMPS. Some parents are reporting this type of burning or oxidative
reaction with TD-DMPS from other pharmacies.)
2. Transdermal
Local – This is a rash where you put the drops on and it is not a problem and
clears up on it’s own
3.
Mercury
Mobilization issue- You may see a rash in places other than where the TD-DMPS
was applied. This is from the mercury being moved around in the body and
mobilized so that it can move out. It will clear up.
(Dr Yasko & many other naturopaths believe any immune enhancement can stimulate a “healing crisis” which can produce a “viral rash”)
“If you don’t know what to do, pray, then follow your gut because
that’s God’s way of speaking to you.” – Dr. Buttar
___________________________________I
stopped adding here!
His research study with ASD kids
-All 31 children were diagnosed (Dx) with Autistic Disorder or PDD
-All children were initially tested for red blood cell metals,
hair metals, mineral levels, urine metal toxicity, and fecal metal toxicity
-All 31 kids showed initial low levels of mercury just like in
cancer patients, the Hg is not readily visible right away. It shows up
later on.
-It would seem logical to just test the feces, since that’s how DMPS
works, but some kids have metals coming out in different ways so we tested
urine and hair and I like lots of testing, at least for my research we did it
that way
-Hair, fecal and urine metals and mineral levels were tested every
2 months (he only did this extreme amount of testing for his study and says you
don’t need to do as much testing as he did if you want to use it on your child)
-After 10 months of using TD-DMPS, the children were tested for
minerals, hair, fecal and urine metals only every 4 months
-All 31 patients showed higher levels of Hg as continuous treatment went on
-As more Hg came out, kids had more improvement in symptoms by
far, even though mercury levels were off the charts
-Treatment was continued until Hg levels finally came back down
DMPS vs. other chelators
-Mercury binds to sulfhydryl groups and DMSA has only one but DMPS
has 2 sulfhydryl groups, making it significantly more effective
-Thus, DMSA is much slower than DMPS at chelating
-DMSA is considered a neurotoxin and makes kids flaccid, or
dead-like looking because of the molecular structure. Have you noticed
this look when your kids are on DMSA?
-DMPS is approved in Europe but DMSA is not because it is a
neurotoxin
-DMPS IV is not good because it is a one-time thing. It is
the slow, continuous pull that makes the difference
-BAL is actually the most effective chelator but can cause death
22% of the time
-EDTA is not good for pulling mercury, EDTA is the best at pulling
cadmium. Cadmium is what may cause hypertension but you can’t pull the
cadmium out well until you have started pulling the mercury out, so if
hypertension is a problem, you need to alternate with TD-DMPS and EDTA
transdermal or suppository. You still need to get the mercury out first if
cadmium is a problem.
-DMPS suppositories work well like transdermal (TD) DMPS but kids
don’t like them and push them out
-Oral DMPS is not absorbed well especially with leaky guts
Blood-Brain Barrier
He’s not sure that there is one. But if there is, DMSA does
cross the barrier and DMPS does not. He likes chelation every 48 hours
because this gives the body time to redistribute the mercury and you deplete a
small amount every other day. It is like removing a little bit of mercury
from a bottle of toxic water then pouring the cleaned water back in the
bottle. The remaining mercury will redistribute itself and all the
molecules will move around so that more can be pulled out. He likes to
chelate every 48 hours for this reason.
IV-DMPS
-If you do this, there are some specific things you need to
follow. Never give an IV push, only give an IV drip.
-You must read
http://www.DMPSbackfire.com/if you wish to do an IV DMPS. He
tells all his patients to read this website before doing an IV DMPS and if they
still want it, to come back. In general, all those doctors reported on
that web site, made big mistakes because they did not know what they were
doing.
-You must find a doctor who is board certified to do an IV
DMPS. Only 186 doctors in USA are board certified for IV DMPS. DMPS
is dangerous when given in an IV form, so make sure you find a doctor who knows
what they are doing.
-Our kids won’t take IV’s and admitting them to the hospital is
costly so IV DMPS doesn’t work
-The half-life of IV-DMPS is much shorter than TD-DMPS, so you are
chelating for a much shorter amount of time with the IV than the lotion.
-Check out
http://www.nomercury.org/for more information
-“Transdermal DMPS is something that any doctor can
prescribe. You don’t need me (Dr. Buttar.) TD is much safer than the
IV. I also have a year-long wait list. Just get any doctor to call
and get the protocol and start taking the prescription right away. You
need to get the metals out as fast as you can.
Dr. Buttar’s protocol for TD-DMPS
-The protocol is available for doctors through AMT pharmacy
-Each drop of TD-DMPS is .987mg of DMPS, so measure per body
weight
-AMT pharmacy will compound the appropriate 4:1 GSH to DMPS
mixture
-For AMT pharmacy, Dose at 1.5mg/kg of body weight every 48 hours
(take child’s weight, convert to kilograms; 1 pound = 0.4536kg OR
you can take child’s weight in pounds and multiply by .682 drops for the
appropriate drops every 48 hours)
-Never exceed 60 drops on any given day regardless of person’s
weight, unless it is for a challenge dose
-A challenge dose is used to collect metal tests of urine, feces,
hair or blood. This is only done no more than once every 2 months.
The amount of TD-DMPS drops should be doubled for the challenge dose and urine
should be collected for the next 12 hours. Feces and blood should be collected
within 24 hours of the challenge.
-At exactly 24 hours after taking the TD-DMPS, you should give the
child double the daily dose of minerals. You should take a multiple
mineral supplement and extra calcium, magnesium is especially important.
Often the regression we sometimes see in these children is not a yeast flare-up
but a magnesium deficiency because DMPS is really good at pulling magnesium
out. Make sure the child is well mineralized on the Off Days. All
mineral supplements are good. I like them all. (MinerALL from http://www.vitalitywellness.com/and Multiple Mineral Complex
Pro-Support as well as Calcium Magnesium Liquid from http://www.KirkmanLabs.com/are good. Dr. Buttar is in the
process of formulating his own mineral formulation but it is not ready yet.)
-place the drops in the child’s hand and have them take their own
medicine by rubbing it on their forearms, biceps, back of knees (stomach,
buttocks, back not good) find a place where veins are showing and have them rub
it in.
-Do not touch the child’s medicine! Get your own! They
need the full dosage and you will be using some if you touch it. Don’t
use gloves because they are made of rubber and have a powder coating, which is
all potentially toxic. You need to stay away from toxins.
Question and Answer session with Dr. Buttar
Q: Should a person do chlorella with DMPS? A: Chlorella is a
natural substance from aquatic sources and sequesters mercury from the
environment. Cilantro also does this. So, it is questionable if these
items are giving your child more mercury in the first place. Just use
DMPS because topical DMPS is being sucked up by the nerves and goes straight
into the brain and by-passes the liver. DMPS completely by-passes the
gut. Topical DMPS is absorbed through the skin. You don’t need
anything else.
Q: Where would high levels of uranium come from and how would you
get rid of it? A: Sources of uranium are multiple. Uranium
could come from water, air, nuclear sites and yes, DMPS chelates it well.
Q: What do you think about hyperbaric chamber therapy (HBOT
– Hyperbaric Oxygen Therapy) used in conjunction with DMPS? A: I’ve had
children with every type of therapy and biomedical treatment imaginable,
including stem cell replacement, in my office as my patients. What these
patients are reporting is that they get better on biomedical interventions,
then level off and don’t improve anymore. But, with DMPS, they keep the
gains because the whole problem is mercury toxicity in the first place.
You don’t want to re-build the brain until you have stopped the degeneration of
brain cells from poison. You don’t want to put a roof on your house while
there is a fire inside. You put the roof back on the house after the fire
is out! After you get rid of the poison that is damaging their brains
(mercury), the kids go right back to where they left off developmentally
and you can start to put the pieces back together and real healing can occur
after that. But, you have to get the poison out first because it is
what’s causing the problem in the first place. There is some research
going on with hyperbarics (HBOT) and they may allow metals to be moved out
maybe, but we don’t know.
Q: Minerals? What when and how much do you give when you are
chelating? A: We didn’t get good results when we were doing DMPS
everyday with Abi. It may have been because mineral depletion was too
severe. We also didn’t move as many metals out. So we dosed DMPS
every other day at the same time. Say, 3:30pm everyday. You do the
minerals exactly 24 hours later, like at 3:30pm and you double the
amount. All minerals are good. There isn’t one that is better than
another. Manganese, Selenium, Zinc are all good. The thyroid and
other metabolic problems come back after getting rid of the Hg. One of my
patients actually had his thyroid come back after a complete non-functioning
thyroid for years. Hormones level off either up or down to their proper
status after proper chelation. I’ve had husbands thank me for giving them
their wives back. Hg causes a reaction in so many metabolic processes
that you even get rid of the detoxification function itself. You don’t
need to prepare a person before hand with minerals, but you can if you
want. I never did. If any mineral is low, we up the dose to 3 or 5
times what that amount should be.
Q: Yeast? How is this caused? A: Yeast is
not caused by DMPS or even DMSA for that matter. The yeast is
caused because they are immunosuppressed. Mercury is an immunosuppressant.
The white blood cells are too low in autism because they are
immunosuppressed. The only people immunosuppressed are Transplant
patients, cancer patients, AIDS and those with autoimmune disorders.
Q: Do you suggest doing Alpha Lipoic Acid (ALA) along with
DMPS? A: You don’t need ALA with DMPS. If a person wants it
that is fine but they don’t need it.
Q: How about special diets to cure autism in conjunction with the
TD-DMPS? A: I never used a special diet on my son. Only 25% of the
kids need a special diet.
Q: Is DMSA a slow chelator then? A: DMPS is 10 times faster
at chelating than DMSA. That extra sulfhydryl group makes it
synergistically a much faster chelator.
Q: Is lead bad and toxic? A: Metals become more toxic the more
you have. They work synergistically when contained together.
DMPS will chelate lead and some cadmium even.
Q: How do you administer TD-DMPS? A: A child takes it, rubs
it in, you put it in their hand not yours. It is almost like they know
they need it. At least it was that way with my son, Abi. Don’t use
a glove because it is latex and may have powder coating – both chemicals you
don’t want to risk using. You rub the child’s arms together if they can’t
do it but THEY TAKE THEIR OWN MEDICINE. DMPS does smell, but you will
learn to deal with it. Put it on the back of the legs, thighs are good,
forearm, biceps are all good. The stomach is not good because you need a
vascular spot (place showing veins.)
Q: I’ve heard that autistic kids have larger head sizes than
normal and decreased blood flow to the brain. Does head size return to
normal and blood flow after TD-DMPS? A: You need to pull the metals
out. The body is trying to get rid of metals by flushing areas out with
blood and possibly restricting blood to other areas as well. Head size
and everything else may heal.
Q: Are there preservatives, like thimerosol, in epidurals and
anesthesia as well as vaccinations? A: Yes, all shots, anesthesia,
epidurals, Rhogam and vaccinations, even the ones that don’t list thimerosol,
still have mercury because they are not required to list it during
manufacturing. An infant may receive more than 60 times the amount of
mercury that is considered safe from one doctor visit with several shots (video
clip presented.)
Q: Is there anything that would keep a person from using DMPS in a
patient, a contraindication? A: Only if a person had an anaphylactic
reaction to it which is extremely rare
Q: Do you use TD-DMPS with amalgams or do you remove them first?
A: Get the mercury out of the body because removing amalgams can be very
expensive. Just chelate the mercury and don’t remove the amalgams.
If you do remove the amalgams, it is a good thing to get an IV-DMPS within 12
hours because the mercury floating around the body is so high, but you can
chelate with the amalgams still in there. They will not disintegrate or
fall apart.
Q: Do you treat yeast before doing TD-DMPS? A: No, we
prescribe anti-fungals during treatment to maintain the yeast gone and use
probiotics, etc. for yeast. Yeast creates an additional stress to the
body but mercury is the underlying issue for immune dysfunction and thus,
yeast.
Q: Do you chelate your son still? A: Maybe one month a
year I chelate him since those with autism have an underlying detoxification
pathway and that is why they are autistic in the first place.
Q: Medications like Risperdol, Zoloft, do you use those with
DMPS? A: Some meds you need to wean off slowly, some you need to
keep on, but most meds, you should just take off cold turkey.
Anti-Seizure meds induce seizures! It says so in the PDR (physicians desk
reference) under side effects. It really could be mercury toxicity that
is causing the seizures in the first place. You need to take out all the
stuff that the body was not meant to have, maybe add a few natural supplements,
but the body heals itself after you get the mercury out.
Q: What if Hg is through the roof on initial testing?
A: Still treat with TD-DMPS, but likely this child will be less severe
ASD because this shows they are excreting. TD-DMPS will help the child
excrete faster.
Q: Is 3 months of treatment on TD-DMPS enough even though the
child is mostly recovered? A: No, 3 months is not enough for
anyone. Even if a child did DMSA for a year or more before starting DMPS,
DMSA is a slow chelator. You must be consistent for at least 6-12 months
on DMPS to remove all the mercury in a partially chelated child. You
don’t want your child to remain even 10% autistic.
Q: Do you use Methyl B12 on your patients? A: Yes, we now
use it in conjunction with TD-DMPS, but did not on the original study.
Q: Are the kids on TD-DMPS for life then? A: Maybe
they need it one month out of 12 (in a pulse mode) for the rest of their life, I
don’t know. They are non-detoxers and need extra help to counteract the
things in the environment.
Q: Do you treat cadmium removal with TD-DMPS? A: No,
get TD-EDTA for cadmium. Use TD-DMPS first to get Hg out, then TD-EDTA
for cadmium or a suppository of EDTA. EDTA is an easier pull of cadmium
than DMPS. Go for the Hg first because it causes the most damage in our
bodies, by far. Then get rid of cadmium. Always treat Hg first,
even if it is lower, much lower than the other metals present.
Q: Do you chelate normal siblings of autistic kids? A: Yes,
you can especially if they have weird physical symptoms or ADD. It is
much more crucial to chelate in a developing brain, than a developed brain.
Q: Do you prefer IV-DMPS? A: I prefer TD-DMPS because
it is slower, safer and a continuous flow. You could do an IV drip once
every other week in addition to the lotion, but it is not crucial.
& I really thought you all will be interested in this email I
received from
Willis Langford after I forwarded him these notes! His response
is in red:
W:I thank you for the Dr. Buttar notes. It contained many great
tidbits.
W:I appreciate you. You are doing great work. Are you and yours
doing TD-DMPS now? What are
you seeing?
So far only our son is on the TD-DMPS for about three months & the first 2 were 2 of the best he’s ever had…but nothing astounding & we seemed to have leveled off again but no signs of him going back down (like he tends to do). I can’t wait to put the whole family on it…but no time yet!
What is amazing though is it muscle tests with some of the best
practitioners out there (Klinghardt & Abell & my babysitter Andy &
Linda) amazing! So were on the
road! But from what Melanie & Tom from College Pharmacy the parents are
raving (testimonials)-
Willis: Here is an interesting tidbit.
The metabolic transmethylation pathways closely interconnect
choline, methionine, folate, as well as vitamins B6 and B12. These metabolic
pathways intersect at the formation of methionine from homocysteine. Perturbing
the metabolism of one of these pathways results in compensatory changes in the
others and may result in one or more deficiencies of the transmethylation
pathway specific nutrients. For example, methionine can be formed from
homocysteine using methyl groups from N5-methyltetrahydrofolate (mTHF), or
using methyl groups from betaine (TMG) that are derived from choline.
Similarly, mTHF can be formed from one-carbon units derived from serine or from
the methyl groups of choline via dimethylglycine (DMG), and choline can be
synthesized de novo using methyl groups derived from methionine (via
S-adenosylmethionine). The availability of transgenic and knockout mice has
made possible additional studies that demonstrate the interrelationship of
these methyl sources. MTHFR knockouts, which have impaired availability of
methyl groups from mTHF, utilize (and consequently deplete) choline and betaine
so as to maintain homocysteine remethylation. As we consider dietary
requirements and possible effects on DNA methylation, it is important to
realize that methionine, mTHF, and choline can be fungible sources of
methyl-groups and the design of future studies should reflect this. (Linda…you were RIGHT!!!)
The impact of alterations in methylation related to methionine, mTHF, and choline deficiency is profound and has been associated with the major diseases of contemporary society, including cancer, cardiovascular diseases, diabetes, neurological disorders, and birth defects. Prior to 1990, numerous studies described the abnormal methylation of DNA in tumors and transformed cells. Less frequently investigated, however, were the exogenous and endogenous agents leading to such abnormal methylation. These included genetic variants among rodent strains and the methyl-deficient diets that caused liver cancer. Carcinogens or other promoters that alter methyl metabolism and/or DNA methylation, such as dichlorodiphenyltrichloroethane (DDT), phenobarbital, arsenic, and zinc deficiency, have been studied and have added to the knowledge about the importance of altered methylation on carcinogenesis. By 1990, a chain of causality had been established in experimental carcinogenesis linking dietary methyl deficiency with methyl insufficiency in vivo, as well as with the abnormal methylation of DNA and of specific genes. Also, during this period, the diminished activity of the enzyme MTHFR, which is responsible for the actual de novo synthesis of methyl groups, was shown to be associated with increased risk of developing atherosclerosis, neurological disorders and birth defects. The exponential rise in studies on methyl metabolism and DNA methylation since then enables us to examine how abnormal methylation processes appear to exert their toxic effects in one disease and how this processes may be applicable to other pathologies.
Love,
Willis
& now you might want to go to Dr Alan Vinitsky’s
“methylation” protocol
but please note…if you are doing folinic acid (broken in small
doses it is better tolerated) & methyl B12 (sub-coetaneous not IM shots –
if pee is red then assume no absorption & it was IM) & it has been
effective continue… but we found the Vintsky protocol seemed really effective.
What you cannot do is sub out folinic for folic or methyl for hydroxo! Think of
two very separate sides of a break…the folic (5mg) & hydroxocobalamin (2mg)
work as a team. The folinic & methyl are on the other side of the break…so
no crossing the break subs.